Synonymous codon usage and variations in the HEAT CONTROL SPRAY level of isoaccepting tRNAs exert a powerful selective force on translation fidelity.We have developed an algorithm to evaluate the relative rate of translation which allows large-scale comparisons of the non-uniform translation rate on the protein biogenesis.Using the complete genomes
Clinical and in vitro models identify distinct adaptations enhancing Staphylococcus aureus pathogenesis in human macrophages.
Staphylococcus aureus is a facultative intracellular pathogen of human macrophages, which facilitates chronic infection.The genotypes, pathways, and mutations influencing that phenotype remain incompletely explored.Here, Powder Foundation we used two distinct strategies to ascertain S.aureus gene mutations affecting pathogenesis in macrophages.Firs